Quarterly guidance

Quarterly guidance
No quarterly guidance was given.

Annual guidance

Revenue
$91 billion to $92 billion
Non-GAAP performance margin
52% to 52.5%
Non-GAAP earnings per share
$35 to $36

Outlook

U.S. Revenue
Expects sustained volume growth in the incretin market and the full-year impact of the Medicare GLP-1 Bridge access and the launch of Foundayo in type 2 diabetes.
International Revenue
Expects Mounjaro's leadership position to continue and the launch of Foundayo to drive additional market growth.
Pricing
Expects net realized price to be a headwind, which will be more than offset by volume growth.
One-time items
2026 revenue benefited from approximately $2 billion of one-time items that are not expected to recur.