Quarterly guidance

Quarterly guidance
No quarterly guidance was given.

Annual guidance

Revenue
$62 billion to $64 billion
R&D expense
$10.8 billion to $11.8 billion
Adjusted diluted EPS
$2.95 to $3.05

Outlook

Non-COVID growth
The company expects continued growth in non-COVID products driven by market performance and new indications.
Cost savings
The company is implementing a second phase of cost savings to deliver $2.5 billion from 2027 to 2029.
Obesity portfolio
Pfizer plans to advance 10 active and planned Phase III trials in 2026 for its obesity portfolio.
Capital allocation
Priorities remain unchanged, focusing on investing in the business, maintaining the dividend, and preserving flexibility for future value-enhancing actions.
LOE transition
Management expects leverage to remain around current levels or modestly higher during the LOE transition period.
Growth target
Pfizer maintains a line of sight to a risk-adjusted high single-digit revenue CAGR from year-end 2028 through year-end 2033.